PRODUCT CODE: ET7106-61

Recombinant IL13 Receptor alpha 1 Monoclonal Antibody (ET7106-61)

  • Recombinant

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

Western blot analysis of IL13 Receptor alpha 1 on A549 cell lysates using anti-IL13 Receptor alpha 1 antibody at 1/500 dilution.
  • Western blot analysis of IL13 Receptor alpha 1 on A549 cell lysates using anti-IL13 Receptor alpha 1 antibody at 1/500 dilution.
  • ICC staining IL13 Receptor alpha 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IL13 Receptor alpha 1 antibody. Counter stained with hematoxylin.
Western blot analysis of IL13 Receptor alpha 1 on A549 cell lysates using anti-IL13 Receptor alpha 1 antibody at 1/500 dilution.

Applications

  • WB

  • ICC

  • IHC-P

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant IL13 Receptor alpha 1 Monoclonal Antibody (ET7106-61)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

A549, HepG2, human liver tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JU38-89

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

50/40 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-2,000

  • ICC

  • 1:100-1:500

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

IL13 Receptor alpha 1

SYNONYMS

bB128O4.2.1 (interleukin 13 receptor, alpha 1) antibody; Cancer/testis antigen 19 antibody; CD213a1 antibody; CD213A1 Antigen antibody; CT 19 antibody; CT19 antibody; I13R1_HUMAN antibody; IL 13 receptor subunit alpha 1 antibody; IL 13R alpha 1 antibody; IL 13R subunit alpha 1 antibody; IL 13Ra antibody; IL 13RA1 antibody; IL-13 receptor subunit alpha-1 antibody; IL-13R subunit alpha-1 antibody; IL-13R-alpha-1 antibody; IL-13RA1 antibody; IL13 receptor alpha 1 chain antibody; IL13R antibody; IL13RA antibody; Il13ra1 antibody; Interleukin 13 receptor alpha 1 antibody; Interleukin 13 receptor alpha 1 chain antibody; interleukin 13 receptor subunit alpha 1 antibody; Interleukin-13 receptor subunit alpha-1 antibody; NR 4 antibody; NR4 antibody

SEQUENCE SIMILARITIES

Belongs to the type I cytokine receptor family. Type 5 subfamily.

TISSUE SPECIFICITY

Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

SUBCELLULAR LOCATION

Membrane.

FUNCTION

Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.