Lane 1: Jurkat cell lysate
Lane 2: rat kidney tissue lysate
Lane 3: rat liver tissue lysate
Lane 4: mouse kidney tissue lysate
Lane 5: human liver tissue lysate
Recombinant Rabbit monoclonal primary
Recombinant GPX4 Monoclonal Antibody (ET1706-45)
Jurkat cell lysate, rat kidney tissue lysate, rat liver tissue lysate, mouse kidney tissue lysate, human liver tissue lysate, zebrafish tissue lysates, rat epididymis tissue, human kidney tissue, mouse testis tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
22 kDa Clone number: JU11-31
Glutathione peroxidase 4 antibody; GPX 4 antibody; GPX-4 antibody; GPX4 antibody; GPX4_HUMAN antibody; GSHPx-4 antibody; MCSP antibody; mitochondrial antibody; PHGPx antibody; Phospholipid hydroperoxidase antibody; Phospholipid hydroperoxide glutathione peroxidase antibody; Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody; snGPx antibody; snPHGPx antibody; Sperm nucleus glutathione peroxidase antibody
Belongs to the glutathione peroxidase family.
Present primarily in testis. Expressed in platelets (at protein level).
Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.