Recombinant Rabbit monoclonal primary
Recombinant FGF2 Monoclonal Antibody (ET1703-18)
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Basic fibroblast growth factor antibody; Basic fibroblast growth factor bFGF antibody; BFGF antibody; FGF 2 antibody; FGF B antibody; FGF-2 antibody; Fgf2 antibody; FGF2 basic antibody; FGF2_HUMAN antibody; FGFB antibody; Fibroblast growth factor 2 (basic) antibody; Fibroblast growth factor 2 antibody; Fibroblast growth factor, basic antibody; HBGF 2 antibody; HBGF-2 antibody; HBGF2 antibody; HBGH 2 antibody; HBGH2 antibody; Heparin binding growth factor 2 precursor antibody; Heparin-binding growth factor 2 antibody; Prostatropin antibody
Belongs to the heparin-binding growth factors family.
Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.; Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.