Positive control:
Lane 1: Hela
Lane 2: PC12
Lane 3: NIH/3T3
Applications
-
WB
-
ICC
-
IF
-
IP
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Recombinant DGCR8 Monoclonal Antibody (ET1609-32)
Immunogen
Recombinant protein
Host
Rabbit
Positive Control
PC12, NIH/3T3, Hela.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
ST04-79
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
100 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:1,000-1:2,000
-
ICC/IF
-
1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
DGCR8
SYNONYMS
DGCRK6 antibody; C22orf12 antibody; D16H22S788E antibody; D16Wis2 antibody; DGCR 8 antibody; Dgcr8 antibody; DGCR8 microprocessor complex subunit antibody; DGCR8_HUMAN antibody; DGCRK 6 antibody; DiGeorge syndrome critical region 8 antibody; DiGeorge syndrome critical region gene 8 antibody; Gy1 antibody; Microprocessor complex subunit DGCR8 antibody; pasha antibody
TISSUE SPECIFICITY
Ubiquitously expressed.
SUBCELLULAR LOCATION
Nucleus.
FUNCTION
DGS8, also designated DiGeorge syndrome critical region 8 protein, plays a role in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS). It is a ubiquitously expressed protein encoded by the gene DGCR8, which is deleted in DiGeorge syndrome. DiGeorge syndrome is characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. In mouse, DGS8 is detected primarily in embryonic brain, vessels, thymus and palate.