Recombinant Rabbit monoclonal primary
Recombinant delta Sarcoglycan Monoclonal Antibody (ET1703-88)
Human lung tissue lysate, human skeletal muscle tissue lysate, human stomach carcinoma tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
35 kDa dystrophin associated glycoprotein antibody; 35 kDa dystrophin-associated glycoprotein antibody; 35DAG antibody; CMD1L antibody; DAGD antibody; Delta-sarcoglycan antibody; Delta-SG antibody; Dystrophin associated glycoprotein delta sarcoglycan antibody; LGMD2F antibody; MGC22567 antibody; Placental delta sarcoglycan antibody; Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody; SG delta antibody; SGCD antibody; SGCD_HUMAN antibody; SGCDP antibody; SGD antibody
Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Glycosylated.; Disulfide bonds are present.
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.