PRODUCT CODE: ET1704-75

Recombinant DAZL Monoclonal Antibody (ET1704-75)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Immunohistochemical analysis of paraffin-embedded rat testes tissue using anti-DAZL antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded rat testes tissue using anti-DAZL antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse testes tissue using anti-DAZL antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded rat testes tissue using anti-DAZL antibody. Counter stained with hematoxylin.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant DAZL Monoclonal Antibody (ET1704-75)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Rat testes tissue, mouse testes tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JA10-36

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

33 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500

  • IHC-P

  • 1:50

TARGET

UNIPROT #

PROTEIN NAME

Deleted in azoospermia-like

GENE NAME

DAZL

SYNONYMS

DAZL, DAZH, DAZL1, DAZLA, SPGYLA

SEQUENCE SIMILARITIES

Belongs to the RRM DAZ family.

TISSUE SPECIFICITY

Testis specific.

SUBCELLULAR LOCATION

Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.

FUNCTION

RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).