Recombinant Ctip1 Monoclonal Antibody (ET7107-38)

Western blot analysis of Ctip1 on Daudi (1) and U937 (2) cell lysate using anti-Ctip1 antibody at 1/500 dilution.

Applications

WB
IHC-P
FC

REACTIVITY

Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant Ctip1 Monoclonal Antibody (ET7107-38)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Daudi, U937, human tonsil tissue, mouse cerebellum tissue, Jurkat.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JB35-68

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

91 kDa

Isotype

IgG

APPLICATION DILUTION

WB
1:500-1:1,000

IHC-P
1:50-1:200

FC
1:50-1:100

TARGET

UNIPROT #

Q9H165

PROTEIN NAME

Ctip1

SYNONYMS

2810047E18Rik antibody; B cell CLL/lymphoma 11A (zinc finger protein) antibody; B cell CLL/lymphoma 11A (zinc finger protein) isoform 2 antibody; B-cell CLL/lymphoma 11A antibody; B-cell lymphoma/leukemia 11A antibody; BC11A_HUMAN antibody; BCL-11A antibody; BCL11A antibody; BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1 antibody; BCL11A L antibody; BCL11A S antibody; BCL11A XL antibody; BCL11a-M antibody; BCL11AL antibody; BCL11AS antibody; BCL11AXL antibody; C2H2 type zinc finger protein antibody; COUP TF interacting protein 1 antibody; COUP-TF-interacting protein 1 antibody; CTIP1 antibody; CTIP1, mouse, homolog of antibody; D930021L15Rik antibody; Ecotropic viral integration site 9 antibody; Ecotropic viral integration site 9 homolog antibody; Ecotropic viral integration site 9 protein antibody; Ecotropic viral integration site 9 protein homolog antibody; EVI-9 antibody; Evi9 antibody; Evi9, mouse, homolog of antibody; FLJ10173 antibody; FLJ34997 antibody; HBFQTL5 antibody; KIAA1809 antibody; mKIAA1809 antibody; OTTHUMP00000159788 antibody; OTTHUMP00000159789 antibody; OTTHUMP00000201250 antibody; OTTHUMP00000202084 antibody; Zinc finger protein 856 antibody; ZNF856 antibody

TISSUE SPECIFICITY

Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.

POST-TRANSLATIONAL MODIFICATION

Sumoylated with SUMO1.

SUBCELLULAR LOCATION

Cytoplasm. Nucleus.

FUNCTION

Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex. Repressor of fetal hemoglobin (HbF) level. Involved in brain development. Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.