Lane 1: mouse brain tissue lysate
Lane 2: mouse cerebrum tissue lysate
Recombinant Rabbit monoclonal primary
Recombinant CNPase Monoclonal Antibody (ET1702-46)
Mouse brain tissue lysate, mouse cerebrum tissue lysate, SHG-44, SH-SY5Y, N2A, mouse brain tissue, rat brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
2' antibody; 2'3' cyclic nucleotide 3' phosphodiesterase antibody; 3'-cyclic-nucleotide 3'-phosphodiesterase antibody; CN37_HUMAN antibody; CNP 1 antibody; CNP antibody; CNP1 antibody; CNPase antibody
Belongs to the 2H phosphoesterase superfamily. CNPase family.
2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.