Lane 1: human heart tissue lysate
Lane 2: mouse heart tissue lysate
Recombinant Rabbit monoclonal primary
Recombinant CD36 Monoclonal Antibody (ET1701-24)
Synthetic peptide within human cd36 aa 350-390.
Human heart tissue lysate, mouse heart tissue lysate, SH-SY5Y, human spleen tissue, THP-1.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
53 kDa (Predicted band size)
Adipocyte membrane protein antibody; BDPLT10 antibody; CD36 antibody; CD36 antigen (collagen type I receptor, thrombospondin receptor) antibody; CD36 antigen antibody; CD36 molecule (thrombospondin receptor) antibody; CD36 molecule antibody; CD36_HUMAN antibody; CHDS7 antibody; Cluster determinant 36 antibody; Collagen receptor, platelet antibody; FAT antibody; Fatty acid translocase antibody; Fatty acid transport protein antibody; Glycoprotein IIIb antibody; GP IIIb antibody; GP3B antibody; GP4 antibody; GPIIIB antibody; GPIV antibody; Leukocyte differentiation antigen CD36 antibody; MGC108510 antibody; MGC91634 antibody; PAS 4 protein antibody; PAS IV antibody; PAS-4 antibody; PASIV antibody; Platelet collagen receptor antibody; Platelet glycoprotein 4 antibody; Platelet glycoprotein IV antibody; scarb3 antibody; Scavenger receptor class B member 3 antibody; Thrombospondin receptor antibody
Belongs to the CD36 family.
N-glycosylated and O-glycosylated with a ratio of 2:1.; Ubiquitinated at Lys-469 and Lys-472. Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome. Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
Cell membrane, Membrane raft, Golgi apparatus, Apical cell membrane.
CD36 (collagen type I receptor, thrombospondin receptor, FAT, GP4, GP3B, GPIV, PASIV, SCARB3) is a membrane glycoprotein on platelets, monocytes and umbilical vein endothelial cells. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. CD36 plays a key role in both phagocytosis and lipid recycling, for constant production of mature spermatozoa. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. Thrombospondins are widely distributed proteins that influence a variety of adhesive processes and CD36 may have important functions as a cell adhesion molecule.