Lane 1: Hela cell lysate
Lane 2: Jurkat cell lysate
Lane 3: human kidney tissue lysate
Recombinant Rabbit monoclonal primary
Recombinant AQP1 Monoclonal Antibody (ET1703-34)
Hela cell lysate, Jurkat cell lysate, human kidney tissue lysate, MCF-7, Hela, SW480, human spleen tissue, human kidney tissue, human breast tissue, human pancreas tissue, mouse colon tissue, mouse skeletal muscle tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
AQP 1 antibody; AQP CHIP antibody; AQP-1 antibody; AQP1 antibody; AQP1_HUMAN antibody; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group) antibody; aquaporin 1 (Colton blood group) antibody; Aquaporin CHIP antibody; Aquaporin-1 antibody; Aquaporin-CHIP antibody; Aquaporin1 antibody; Channel forming integral protein 28kDa antibody; Channel like integral membrane protein 28 kDa antibody; CHIP 28 antibody; CHIP28 antibody; CO antibody; Colton blood group antibody; Growth factor induced delayed early response protein antibody; MGC26324 antibody; Urine water channel antibody; Water channel protein CHIP 29 antibody; Water channel protein CHIP29 antibody; Water channel protein for red blood cells and kidney proximal tubule antibody
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of Aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most Aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP1 is an integral membrane protein expressed in erythrocytes and renal tubule cells.