PRODUCT CODE: ET1705-47

Recombinant alpha 1 Antichymotrypsin Monoclonal Antibody (ET1705-47)

  • Recombinant

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

Western blot analysis of alpha 1 Antichymotrypsin on human serum using anti-alpha 1 Antichymotrypsin antibody at 1/1,000 dilution.
  • Western blot analysis of alpha 1 Antichymotrypsin on human serum using anti-alpha 1 Antichymotrypsin antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-alpha 1 Antichymotrypsin antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-alpha 1 Antichymotrypsin antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-alpha 1 Antichymotrypsin antibody. Counter stained with hematoxylin.
Western blot analysis of alpha 1 Antichymotrypsin on human serum using anti-alpha 1 Antichymotrypsin antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Recombinant alpha 1 Antichymotrypsin Monoclonal Antibody (ET1705-47)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human serum, human tonsil tissue, human prostate tissue, human placenta tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JM83-29

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

60 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

alpha 1 Antichymotrypsin

SYNONYMS

SERPINA3 antibody; AACT antibody; AACT_HUMAN antibody; ACT antibody; Alpha-1-antichymotrypsin His-Pro-less antibody; Antichymotrypsin antibody; Cell growth inhibiting gene 24/25 protein antibody; Cell growth-inhibiting gene 24/25 protein antibody; GIG24 antibody; GIG25 antibody; Growth inhibiting protein 24 antibody; Growth inhibiting protein 25 antibody; MGC88254 antibody; Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3 antibody; Serine (or cysteine) proteinase inhibitor clade A member 3 antibody; Serine proteinase inhibitor clade A member 3 antibody; Serpin A3 antibody; Serpin family A member 3 antibody; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 antibody; SERPINA3 antibody

SEQUENCE SIMILARITIES

Belongs to the serpin family.

TISSUE SPECIFICITY

Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.

POST-TRANSLATIONAL MODIFICATION

N- and O-glycosylated.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.