Recombinant Rabbit monoclonal primary
Recombinant OS9 Monoclonal Antibody (ET7108-61)
Recombinant protein of c-terminal human os9.
Mouse testis tissue lysate, rat testis tissue lysate, rat epididymis tissue, human breast cancer tissue, human placenta tissue, mouse testis tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Belongs to the OS-9 family.
Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines. Isoform 2 is the major isoform detected in all cell types examined.
Intramolecular disulfide bonds.; Isoform 1 and isoform 2 are N-glycosylated.
Endoplasmic reticulum lumen.
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.