Rabbit polyclonal primary
RBPMS Antibody (ER1901-43)
Synthetic peptide within n-terminal human rbpms.
Mouse lung tissue lysates, A431, F9, rat smooth muscle tissue, rat kidney tissue, mouse lung tissue, mouse brain tissue, mouse kidney tissue, mouse fallopian tube tissue, mouse heart tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size 22 kDa.
RNA-binding protein with multiple splicing
Ubiquitously expressed, at various levels depending on the isoform and the tissue.
Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Translocates into cytoplasmic stress granules that probably correspond to P-bodies in response to oxidative stress.
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.