Lane 1: PC12
Lane 2: MCF-7
Lane 3: 293T
Lane 4: Mouse brain
Lane 5: Mouse intestine
Lane 6: Rat brain
Rabbit polyclonal primary
Ras Antibody (ER40115)
PC12, MCF-7, 293T, Hela, HepG2, mouse brain tissue, mouse intestines tissue, rat brain tissue, human kidney tissue, mouse kidney tissue, mouse small intestine tissue, mouse pancreas tissue, rat kidney tissue, rat small intestine tissue, human liver cancer tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
Belongs to the small GTPase superfamily. Ras family.
Palmitoylated by the ZDHHC9-GOLGA7 complex. Depalmitoylated by ABHD17A, ABHD17B and ABHD17C. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.; Acetylation at Lys-104 prevents interaction with guanine nucleotide exchange factors (GEFs).; Ubiquitinated by the BCR(LZTR1) E3 ubiquitin ligase complex at Lys-170 in a non-degradative manner, leading to inhibit Ras signaling by decreasing Ras association with membranes.; Phosphorylation at Ser-89 by STK19 enhances NRAS-association with its downstream effectors.
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus.
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Qiu, Qiang et al.
Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma. | Oncotarget 
Shen, Junyi et al.
Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway. | Aging