Rabbit polyclonal primary
RAB27B Antibody (ER2001-10)
Synthetic peptide with n-terminal human rab27b.
U937 cell lysates, A549.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Late endosome, Membrane, Lipid-anchor.
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion ref. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 ref. May be involved in targeting uroplakins to urothelial apical membranes (By similarity).