Positive control:
Lane 1: SK-Br-3 cell lysate
Lane 2: K562 cell lysate
Applications
-
WB
-
FC
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
PYCR1 Antibody (ER2001-18)
Immunogen
Synthetic peptide within human pycr1 aa 220-260.
Host
Rabbit
Positive Control
SK-Br-3 cell lysate, K562 cell lysate, HepG2.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified.
MOLECULAR WEIGHT
33 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:2,000
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
PYCR1
SYNONYMS
P5C antibody; P5C reductase 1 antibody; P5C reductase antibody; P5CR 1 antibody; P5CR antibody; PIG45 antibody; PP222 antibody; Proliferation inducing protein 45 antibody; PYCR 1 antibody; PYCR antibody; Pyrroline 5 carboxylate reductase 1 antibody; Pyrroline 5 carboxylate reductase 1 mitochondrial antibody
SUBCELLULAR LOCATION
Mitochondrion.
FUNCTION
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants.