Lane 1: Hela cell lysate
Lane 2: 293 cell lysate
Lane 3: Mouse cerebellum tissue lysate
Lane 4: Mouse liver tissue lysate
Lane 5: Rat liver tissue lysate
Rabbit polyclonal primary
PSMA5 Antibody (ER2001-68)
Recombinant protein within human psma5 aa 1-200.
Hela cell lysate, 293 cell lysate, mouse cerebellum tissue lysate, mouse liver tissue lysate, rat liver tissue lysate, human liver carcinoma tissue, human colon carcinoma tissue.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Proteasome subunit alpha type-5 Macropain zeta chain Multicatalytic endopeptidase complex zeta chain Proteasome zeta chain
Cytoplasm, Nucleus, Proteasome.
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).