PRODUCT CODE: ER1706-96

PFAS Antibody (ER1706-96)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

-
+
Western blot analysis of PFAS on Hela cell lysate using anti-PFAS antibody at 1/1,000 dilution.
  • Western blot analysis of PFAS on Hela cell lysate using anti-PFAS antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PFAS antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PFAS antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-PFAS antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PFAS antibody. Counter stained with hematoxylin.
Western blot analysis of PFAS on Hela cell lysate using anti-PFAS antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

PFAS Antibody (ER1706-96)

Immunogen

Recombinant protein within human purl aa 1173-1338.

Host

Rabbit

Positive Control

Hela, human tonsil tissue, human spleen tissue, human breast tissue, human kidney tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein affinity purified

MOLECULAR WEIGHT

145 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

PFAS

SYNONYMS

PFAS antibody; FGAM synthase antibody; FGAMS antibody; FGAR amidotransferase antibody; FGARAT antibody; Formylglycinamide ribotide amidotransferase antibody; Formylglycinamide ribotide synthetase antibody; KIAA0361 antibody; Phosphoribosylformylglycinamidine synthase antibody; PURL antibody

SEQUENCE SIMILARITIES

In the N-terminal section; belongs to the FGAMS family.

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis.