Applications
-
WB
-
IHC-P
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
PFAS Antibody (ER1706-96)
Immunogen
Recombinant protein within human purl aa 1173-1338.
Host
Rabbit
Positive Control
Hela, human tonsil tissue, human spleen tissue, human breast tissue, human kidney tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein affinity purified
MOLECULAR WEIGHT
145 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500
-
IHC-P
-
1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
PFAS
SYNONYMS
PFAS antibody; FGAM synthase antibody; FGAMS antibody; FGAR amidotransferase antibody; FGARAT antibody; Formylglycinamide ribotide amidotransferase antibody; Formylglycinamide ribotide synthetase antibody; KIAA0361 antibody; Phosphoribosylformylglycinamidine synthase antibody; PURL antibody
SEQUENCE SIMILARITIES
In the N-terminal section; belongs to the FGAMS family.
SUBCELLULAR LOCATION
Cytoplasm.
FUNCTION
Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis.