PRODUCT CODE: ER1802-11

PBR Antibody (ER1802-11)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

Western blot analysis of PBR on A431 and PC-3M cell lysateS using anti-PBR antibody at 1/500 dilution.<br />
  • Western blot analysis of PBR on A431 and PC-3M cell lysateS using anti-PBR antibody at 1/500 dilution.<br />
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PBR antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PBR antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PBR antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-PBR antibody. Counter stained with hematoxylin.
Western blot analysis of PBR on A431 and PC-3M cell lysateS using anti-PBR antibody at 1/500 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

PBR Antibody (ER1802-11)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

A431, PC-3M, human colon cancer tissue, human kidney tissue, mouse colon tissue, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein affinity purified

MOLECULAR WEIGHT

10/18 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Translocator protein

GENE NAME

TSPO

SYNONYMS

PBR, TSPO, BZRP, MBR

SEQUENCE SIMILARITIES

Belongs to the TspO/BZRP family.

TISSUE SPECIFICITY

Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.

SUBCELLULAR LOCATION

Mitochondrion membrane; Multi-pass membrane protein.

FUNCTION

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism.