Lane 1: HepG2
Lane 2: Hela
Recombinant Rabbit monoclonal primary
PAX9 Recombinant Rabbit Monoclonal Antibody [SD082-02] (ET1612-59)
Recombinant protein within human pax9 aa 6-120 / 341.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Paired box 9 antibody; Paired box gene 9 antibody; Paired box homeotic gene 9 antibody; Paired box protein 9 antibody; Paired box protein Pax 9 antibody; Paired box protein Pax-9 antibody; Paired box protein Pax9 antibody; Paired domain gene 9 antibody; PAX 9 antibody; PAX9 antibody; PAX9_HUMAN antibody; STHAG3 antibody
Pax genes contain paired domains with strong homology to genes in Droso-phila which are involved in programming early development. Pax-9, a member of the paired box-containing gene family, is closely related in its paired do-main to Pax-1. The Pax-9 gene encodes the highly conserved paired domain and the gene is a member of the same subgroup as Pax-1/undulated. Pax-9 is essential for the development of a variety of organs and skeletal elements. Mutations in either the Pax-1 or the Pax-9 genes may produce an inherited skeletal disorder such as the Jarcho-Levin syndrome or other forms of spondylocostal dysplasia, conditions resembling “undulated” in the mouse. A frameshift mutation within the paired domain of Pax-9 was identified in a family segregating autosomal dominant oligodontia whose members had normal primary dentition but lacked most permanent molars. In addition to lack of permanent molars, some individuals also lacked maxillary and/or mandibular second premolars, as well as mandibular central incisors. The gene which encodes Pax-9 maps to human chromosome 14q12-q13.