Applications
-
WB
-
IHC-P
-
FC
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Mouse monoclonal primary
Product Name
ORM1 Monoclonal Antibody (EM1510-41)
Immunogen
Full length of recombinant protein of human alpha-1-acid glycoprotein.
Host
Mouse
Positive Control
Recombinant protein, rat liver tissue, human lung cancer tissue, mouse liver tissue, human esophagus tissue, HepG2.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
A2-B10
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 ug/ul
PURIFICATION
ProG purified.
MOLECULAR WEIGHT
24 kDa (Predicted band size)
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500
-
IHC-P
-
1:50-1:200
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
ORM1
SYNONYMS
A1AG1_HUMAN antibody; AGP 1 antibody; AGP A antibody; AGP antibody; AGP1 antibody; Alpha 1 acid glycoprotein antibody; Alpha-1-acid glycoprotein 1 antibody; alpha-1-AGP antibody; Epididymis secretory sperm binding protein Li 153w antibody; glycoprotein, alpha-1-acid, of serum antibody; HEL S 153w antibody; OMD 1 antibody; ORM antibody; ORM1 antibody; Orosomucoid 1 antibody; Orosomucoid-1 antibody
SEQUENCE SIMILARITIES
Belongs to the calycin superfamily. Lipocalin family.
TISSUE SPECIFICITY
Expressed by the liver and secreted in plasma.
POST-TRANSLATIONAL MODIFICATION
N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.