PRODUCT CODE: EM1701-54

MAOA Monoclonal Antibody (EM1701-54)

Applications

  • WB

  • ICC

REACTIVITY

  • Human

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Western blot analysis of Monoamine Oxidase A on human liver tissue lysates using anti- Monoamine Oxidase A antibody at 1/1,000 dilution.
  • Western blot analysis of Monoamine Oxidase A on human liver tissue lysates using anti- Monoamine Oxidase A antibody at 1/1,000 dilution.
  • ICC staining Monoamine Oxidase A in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Western blot analysis of Monoamine Oxidase A on human liver tissue lysates using anti- Monoamine Oxidase A antibody at 1/1,000 dilution.

Applications

  • WB

  • ICC

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

MAOA Monoclonal Antibody (EM1701-54)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

human liver tissue lysates, SH-SY-5Y.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

5D1

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein G purified.

MOLECULAR WEIGHT

60 kDa

Isotype

IgG1

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • ICC

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

MAOA

SYNONYMS

Amine oxidase [flavin containing] A antibody; Amine oxidase [flavin-containing] A antibody; AOFA antibody; AOFA_HUMAN antibody; EC 1.4.3.4 antibody; MAO A antibody; MAO-A antibody; maoA antibody; Monoamine oxidase A antibody; Monoamine oxidase type A antibody

SEQUENCE SIMILARITIES

Belongs to the flavin monoamine oxidase family.

TISSUE SPECIFICITY

Heart, liver, duodenum, blood vessels and kidney.

SUBCELLULAR LOCATION

Mitochondrion outer membrane.

FUNCTION

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. Has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.