Applications
-
WB
-
ICC
REACTIVITY
-
Human
SPECIFICATIONS
Product Type
Mouse monoclonal primary
Product Name
MAOA Monoclonal Antibody (EM1701-54)
Immunogen
Recombinant protein
Host
Mouse
Positive Control
human liver tissue lysates, SH-SY-5Y.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
5D1
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 ug/ul
PURIFICATION
Protein G purified.
MOLECULAR WEIGHT
60 kDa
Isotype
IgG1
APPLICATION DILUTION
-
WB
-
1:500-1:2,000
-
ICC
-
1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
MAOA
SYNONYMS
Amine oxidase [flavin containing] A antibody; Amine oxidase [flavin-containing] A antibody; AOFA antibody; AOFA_HUMAN antibody; EC 1.4.3.4 antibody; MAO A antibody; MAO-A antibody; maoA antibody; Monoamine oxidase A antibody; Monoamine oxidase type A antibody
SEQUENCE SIMILARITIES
Belongs to the flavin monoamine oxidase family.
TISSUE SPECIFICITY
Heart, liver, duodenum, blood vessels and kidney.
SUBCELLULAR LOCATION
Mitochondrion outer membrane.
FUNCTION
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. Has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.