PRODUCT CODE: 0807-6

LT-alpha(C-term) Antibody (0807-6)

Applications

  • WB

REACTIVITY

  • Human

  • Rat

Western blot analysis on LT-alpha(TNF-β) using anti- LT-alpha polyclonal antibody
  • Western blot analysis on LT-alpha(TNF-β) using anti- LT-alpha polyclonal antibody
Western blot analysis on LT-alpha(TNF-β) using anti- LT-alpha polyclonal antibody

Applications

  • WB

REACTIVITY

  • Human

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

LT-alpha(C-term) Antibody (0807-6)

Immunogen

Peptide

Host

Rabbit

Positive Control

LT-alpha(TNF-beta)

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

18 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000

TARGET

UNIPROT #

PROTEIN NAME

Lymphotoxin-alpha

GENE NAME

LTA

SYNONYMS

LT-alpha

SEQUENCE SIMILARITIES

Belongs to the tumor necrosis factor family.

SUBCELLULAR LOCATION

Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated.

FUNCTION

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.