Lane 1: MCF-7
Lane 2: Mouse marrow
Rabbit polyclonal primary
KV4.3 Antibody (ER1802-91)
Synthetic peptide within human kv4.3 440-480 aa.
MCF-7, mouse marrow tissue, LOVO, MG-63, human esophagus tissue, human placenta tissue, mouse cerebellum tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
KCND 3 antibody; KCND 3L antibody; KCND 3S antibody; Kcnd3 antibody; KCND3_HUMAN antibody; KCND3L antibody; KCND3S antibody; KSHIVB antibody; Kv 4.3 antibody; MGC14203 antibody; MGC142037 antibody; OTTHUMP00000063948 antibody; Potassium ioinic channel Kv4.3 antibody; Potassium voltage gated channel Shal related subfamily member 3 antibody; Potassium voltage gated channel subfamily D member 3 antibody; Potassium voltage-gated channel subfamily D member 3 antibody; Sha1 related potassium channel Kv4.3 antibody; Voltage gated K+ channel antibody; Voltage gated potassium channel Kv4.3 antibody; Voltage gated potassium channel subunit Kv4.3 antibody; Voltage-gated potassium channel subunit Kv4.3 antibody
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.
Regulated through phosphorylation at Ser-569 by CaMK2D.
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.