PRODUCT CODE: M1305-3

Interleukin 31 Monoclonal Antibody (M1305-3)

Applications

  • WB

  • ELISA

REACTIVITY

  • Human

Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).
  • Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).
Western blot analysis on bioactive recombinant human IL-31 protein using anti-IL-31 Mouse mAb (Cat. # M1305-3).

Applications

  • WB

  • ELISA

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

Interleukin 31 Monoclonal Antibody (M1305-3)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

Bioactive recombinant human IL-31 protein

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

B7-B0

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

18kDa

Isotype

IgG2a

APPLICATION DILUTION

  • WB

  • 1:2,000

  • ELISA

  • 1:5,000-1:10,000

TARGET

UNIPROT #

PROTEIN NAME

Interleukin-31

GENE NAME

IL31

SYNONYMS

IL-31

TISSUE SPECIFICITY

Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro (By similarity). Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity).