Applications
-
IHC-P
-
ELISA
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Mouse monoclonal primary
Product Name
Insulin Monoclonal Antibody (EM80714)
Immunogen
Peptide
Host
Mouse
Positive Control
Rat pancreas tissue, human pancreas tissue, Insulin recombinant protein.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
A6-6
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
12 kDa
Isotype
IgG1
APPLICATION DILUTION
-
IHC-P
-
1:100-1:1,000
-
ELISA
-
1:10,000
TARGET
UNIPROT #
PROTEIN NAME
Insulin
SYNONYMS
IDDM antibody; IDDM1 antibody; IDDM2 antibody; ILPR antibody; ins antibody; INS_HUMAN antibody; Insulin A chain antibody; Insulin B chain antibody; IRDN antibody; MODY10 antibody; Preproinsulin antibody; Proinsulin antibody; Proinsulin precursor antibody
SEQUENCE SIMILARITIES
Belongs to the insulin family.
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's cells to take up glucose from the blood (including liver, muscle, and fat tissue cells), storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide.