Insulin Monoclonal Antibody (EM80714)

Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using anti-Insulin antibody. Counter stained with hematoxylin.

Applications

IHC-P
ELISA

REACTIVITY

Human
Mouse
Rat

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

Insulin Monoclonal Antibody (EM80714)

Immunogen

Peptide

Host

Mouse

Positive Control

Rat pancreas tissue, human pancreas tissue, Insulin recombinant protein.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A6-6

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

12 kDa

Isotype

IgG1

APPLICATION DILUTION

IHC-P
1:100-1:1,000

ELISA
1:10,000

TARGET

UNIPROT #

P01308

PROTEIN NAME

Insulin

SYNONYMS

IDDM antibody; IDDM1 antibody; IDDM2 antibody; ILPR antibody; ins antibody; INS_HUMAN antibody; Insulin A chain antibody; Insulin B chain antibody; IRDN antibody; MODY10 antibody; Preproinsulin antibody; Proinsulin antibody; Proinsulin precursor antibody

SEQUENCE SIMILARITIES

Belongs to the insulin family.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's cells to take up glucose from the blood (including liver, muscle, and fat tissue cells), storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide.