PRODUCT CODE: ER1706-26

IL17RB Antibody (ER1706-26)

Applications

  • WB

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of IL17RB on different lysates using anti-IL17RB antibody at 1/1,000 dilution.<br />
  Positive control:<br />
  Lane 1: Mouse liver tissue <br />
  Lane 2: Human kidney tissue <br />
  Lane 3: Rat kidney tissue <br />
  Lane 4: SiHa
  • Western blot analysis of IL17RB on different lysates using anti-IL17RB antibody at 1/1,000 dilution.<br />
  Positive control:<br />
  Lane 1: Mouse liver tissue <br />
  Lane 2: Human kidney tissue <br />
  Lane 3: Rat kidney tissue <br />
  Lane 4: SiHa
Western blot analysis of IL17RB on different lysates using anti-IL17RB antibody at 1/1,000 dilution.
Positive control:
Lane 1: Mouse liver tissue
Lane 2: Human kidney tissue
Lane 3: Rat kidney tissue
Lane 4: SiHa

Applications

  • WB

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

IL17RB Antibody (ER1706-26)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Mouse liver tissue lysate, human kidney tissue lysate, rat kidney tissue lysate, SiHa.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

56 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

TARGET

UNIPROT #

PROTEIN NAME

IL17RB

SYNONYMS

CRL 4 antibody; CRL4 antibody; Cytokine receptor CRL4 antibody; EVI 27 antibody; EVI27 antibody; IL 17 receptor B antibody; IL 17 receptor homolog 1 antibody; IL 17B receptor antibody; IL 17RB antibody; IL 17Rh1 antibody; IL17BR antibody; IL17RB antibody; IL17RH1 antibody; Interleukin 17 receptor B antibody; Interleukin 17 receptor homolog 1 antibody; Interleukin 17 receptor homolog antibody; Interleukin 17B receptor antibody; MGC5245 antibody

TISSUE SPECIFICITY

Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

SUBCELLULAR LOCATION

Single-pass type I membrane protein. Secreted.

FUNCTION

Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RB is a member of the cytokine receptor family and acts as a receptor for the proinflammatory cytokines IL-17B and IL-17E. It may play a role in hematopoietic cell differentiation and growth. IL-17RB expression is high in liver, colon, brain, kidney and testis. IL-17RB is detected in fibroblast-like synoviocytes of rheumatoid arthritis patients.