PRODUCT CODE: 0804-9

IL-7R-alpha Antibody (0804-9)

Applications

  • WB

  • ICC

  • IHC-P

  • FC

REACTIVITY

  • Human

Western blot analysis on K562(A) and human skin tissue (B)using anti- IL-7R-alpha polyclonal antibody.
  • Western blot analysis on K562(A) and human skin tissue (B)using anti- IL-7R-alpha polyclonal antibody.
Western blot analysis on K562(A) and human skin tissue (B)using anti- IL-7R-alpha polyclonal antibody.

Applications

  • WB

  • ICC

  • IHC-P

  • FC

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

IL-7R-alpha Antibody (0804-9)

Immunogen

Peptide

Host

Rabbit

Positive Control

Skin tissue

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

52/34/30/75kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000-5,000

TARGET

UNIPROT #

PROTEIN NAME

IL-7R-alpha

SYNONYMS

CD 127 antibody; CD127 antibody; CD127 antigen antibody; CDw127 antibody; IL 7R alpha antibody; IL 7R antibody; IL-7 receptor subunit alpha antibody; IL-7R subunit alpha antibody; IL-7R-alpha antibody; IL-7RA antibody; IL7R antibody; IL7RA antibody; IL7RA_HUMAN antibody; IL7Ralpha antibody; ILRA antibody; Interleukin 7 receptor alpha chain antibody; Interleukin 7 receptor antibody; Interleukin 7 receptor isoform H5 6 antibody; Interleukin-7 receptor subunit alpha antibody

SEQUENCE SIMILARITIES

Belongs to the type I cytokine receptor family. Type 4 subfamily.

POST-TRANSLATIONAL MODIFICATION

N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form.

SUBCELLULAR LOCATION

Secretion protein/Cell membrane

FUNCTION

The IL-7 cytokine plays a major role in the in vivo maintenance of polyclonal naive and memory T cells, positively regulating the survival, differentiation and proliferation of thymocyte and peripheral T lymphocyte populations. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor γ chain common to the IL-2, IL-4,IL-7, IL-9 and IL-15 receptors. Soluble forms of the IL-7 Rα have been reported.