Lane 1: A172 cell lysate
Lane 2: K562 cell lysate
Rabbit polyclonal primary
IFITM1 Antibody (ER2001-46)
Synthetic peptide within human ifitm1 aa 1-50.
A172 cell lysate, K562 cell lysate.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
9-27 antibody; CD 225 antibody; CD 225 antigen antibody; CD225 antibody; CD225 antigen antibody; Dispanin subfamily A member 2a antibody; DSPA2a antibody; IFI 17 antibody; IFI17 antibody; IFITM1 antibody; IFM1_HUMAN antibody; Interferon induced protein 17 antibody; interferon induced transmembrane protein 1 (9-27) antibody; Interferon induced transmembrane protein 1 antibody; Interferon inducible protein 9-27 antibody; Interferon-induced protein 17 antibody; Interferon-induced transmembrane protein 1 antibody; Interferon-inducible protein 9-27 antibody; Leu 13 antibody; Leu 13 antigen antibody; Leu-13 antigen antibody; LEU13 antibody
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.