Mouse monoclonal primary
HNP-1 Monoclonal Antibody (EM1701-52)
Rat spleen tissue, human spleen tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein G purified.
Neutrophil defensin 1
HP-1, HP1, HP-2, HP2, DEFA1, DEF1, DEFA2, MRS
Belongs to the alpha-defensin family.
ADP-ribosylation drastically reduces cytotoxic and antibacterial activities, and enhances IL8 production.; Phosphorylation at Tyr-85 has been found in some cancer cell lines, and interferes with ADP-ribosylation.
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.