Positive control:
Lane 1: Siha
Lane 2: Hela
Lane 3: A549
Lane 4: Mouse kidney tissue
Lane 5: Rat liver tissue
Applications
-
WB
-
ICC
-
IHC-P
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
GST3 Antibody (ER1802-63)
Immunogen
Recombinant protein with human gst3 aa 1-150.
Host
Rabbit
Positive Control
Siha, Hela, A549, mouse kidney tissue lysate, rat liver tissue lysate, HUVEC, LOVO, human liver cancer tissue, human placenta tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein affinity purified.
MOLECULAR WEIGHT
23 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:1,000
-
ICC
-
1:500-1:1,000
-
IHC-P
-
1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
GST3
SYNONYMS
Deafness antibody; Deafness X-linked 7 antibody; DFN7 antibody; FAEES3 antibody; Fatty Acid Ethyl Ester Synthase III antibody; Glutathione S Transferase 3 antibody; Glutathione S Transferase Pi antibody; Glutathione S-transferase P antibody; Glutathione S-transferase pi 1 antibody; GST class-pi antibody; GST3 antibody; GSTP antibody; Gstp1 antibody; GSTP1-1 antibody; GSTP1_HUMAN antibody; PI antibody; X linked 7 antibody
SEQUENCE SIMILARITIES
Belongs to the GST superfamily. Pi family.
SUBCELLULAR LOCATION
Nucleus. Cytoplasm. Mitochondrion.
FUNCTION
Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.