Positive control:
Lane 1: Mouse marrow tissue lysate
Lane 2: HUVEC cell lysate
Lane 3: 293 cell lysate
Lane 4: Rat marrow tissue lysate
Applications
-
WB
-
IHC
-
FC
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
GRK1 Antibody (ER2001-72)
Immunogen
Synthetic peptide within human grk1 aa 500-563.
Host
Rabbit
Positive Control
Mouse marrow tissue lysate, HUVEC cell lysate, 293 cell lysate, rat marrow tissue lysate, mouse eyeball tissue, rat eyeball tissue, SHSY5Y.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified.
MOLECULAR WEIGHT
Predicted band size: 63 kDa.
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:1,000
-
IHC
-
1:100-1:500
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
GRK1
SYNONYMS
EC=2.7.11.14 antibody; G protein-coupled receptor kinase 1 antibody; GPRK1 antibody; Grk1 antibody; Rhodopsin kinase antibody; RHOK antibody; RK antibody; RK_HUMAN antibody
SUBCELLULAR LOCATION
Cell projection, Membrane.
FUNCTION
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).