Rabbit polyclonal primary
GABRB1 Antibody (ER1901-66)
Synthetic peptide within rat gabrb1 aa 300-400.
Rat brain tissue lysates, 293T, LOVO, rat kidney tissue, human skin tissue, human breast tissue, human breast carcinoma tissue, human kidney tissue, mouse kidney tissue, mouse heart tissue, SH-SY5Y.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size 54 kDa.
Gamma-aminobutyric acid receptor subunit beta-1
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.