PRODUCT CODE: 0905-1

FAT tumor suppressor homolog 4 Antibody (0905-1)

Applications

  • WB

  • ICC

REACTIVITY

  • Human

Western blot analysis on recombinant FAT4 using anti-FAT4 polyclonal antibody.
  • Western blot analysis on recombinant FAT4 using anti-FAT4 polyclonal antibody.
  • ICC image of FAT4 antibody stained D3 (Murine Embryonic Stem Cell Line).The secondary antibody (red) was goat anti-rabbit IgG (H+L) alexa555 conjugated.
Western blot analysis on recombinant FAT4 using anti-FAT4 polyclonal antibody.

Applications

  • WB

  • ICC

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

FAT tumor suppressor homolog 4 Antibody (0905-1)

Immunogen

Peptide

Host

Rabbit

Positive Control

Recombinant protein D3(Murine Embryomic Stem Cell Line)

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

48 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB:1:500-1:1,000

  • ICC

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

Protocadherin Fat 4

GENE NAME

FAT4

SYNONYMS

hFat4

TISSUE SPECIFICITY

Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.

DEVELOPMENTAL STAGE

In embryos at 9 weeks the strongest expression is detected in the apical neuroepithelium, with weaker staining being present in the subventricular zone and within the cortical plate.

SUBCELLULAR LOCATION

Membrane; Single-pass type I membrane protein. Note=In the kidney, localizes to primary cilia.

FUNCTION

Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity).