Rabbit polyclonal primary
FAT tumor suppressor homolog 4 Antibody (0905-1)
Recombinant protein D3(Murine Embryomic Stem Cell Line)
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Immunogen affinity purified
Protocadherin Fat 4
Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.
In embryos at 9 weeks the strongest expression is detected in the apical neuroepithelium, with weaker staining being present in the subventricular zone and within the cortical plate.
Membrane; Single-pass type I membrane protein. Note=In the kidney, localizes to primary cilia.
Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity).