PRODUCT CODE: 0810-1

FADD Antibody (0810-1)

Applications

  • WB

  • FC

REACTIVITY

  • Mouse

Western blot analysis on mouse heart lysates using anti-FADD polyclonal antibody
  • Western blot analysis on mouse heart lysates using anti-FADD polyclonal antibody
Western blot analysis on mouse heart lysates using anti-FADD polyclonal antibody

Applications

  • WB

  • FC

REACTIVITY

  • Mouse

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

FADD Antibody (0810-1)

Immunogen

Peptide

Host

Rabbit

Positive Control

Mouse heart

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

27 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:2,000

TARGET

UNIPROT #

PROTEIN NAME

FAS-associated death domain protein

GENE NAME

Fadd

SYNONYMS

FADD

POST-TRANSLATIONAL MODIFICATION

Phosphorylated.

FUNCTION

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).