Rabbit polyclonal primary
Eg5 Antibody (ER1803-25)
Recombinant protein within human eg5 aa 100-300.
A431, SH-SY-5Y, SiHa, rat kidney tissue, human lung cancer tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Kinesin-like protein KIF11
TR-interacting protein 5, TRIP-5, KIF11, EG5, KNSL1, TRIP5
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily.
Phosphorylated exclusively on serine during S phase, but on both serine and Thr-926 during mitosis, so controlling the association of KIF11 with the spindle apparatus (probably during early prophase).; A subset of this protein primarily localized at the spindle pole is phosphorylated by NEK6 during mitosis; phosphorylation is required for mitotic function.
Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.