Rabbit polyclonal primary
DPP6 Antibody (ER1902-07)
Synthetic peptide within human dpp6 aa 400-500.
Rat brain tissue lysates, F9, SHG-44, N2A, rat brain tissue, mouse brain tissue, SHSY5Y.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size 97 kDa.
Dipeptidyl aminopeptidase IV related protein antibody; Dipeptidyl aminopeptidase like protein 6 antibody; Dipeptidyl aminopeptidase related protein antibody; Dipeptidyl peptidase 6 antibody; Dipeptidyl peptidase IV like protein antibody; Dipeptidyl peptidase IV related protein antibody; Dipeptidylpeptidase 6 antibody; Dipeptidylpeptidase VI antibody; DPP VI antibody; DPPX antibody; VF2 antibody
Belongs to the peptidase S9B family.
Expressed predominantly in brain.
Promotes cell surface expression of the potassium channel KCND2 . Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity .This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.