Applications
-
IHC-P
REACTIVITY
-
Zebrafish
SPECIFICATIONS
Product Type
Mouse monoclonal primary
Product Name
ddx24 Monoclonal Antibody (EM1902-03)
Immunogen
Recombinant protein within zebrafish ddx24 aa 550-820.
Host
Mouse
Positive Control
Zebrafish tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
A3B10
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 ug/ul
PURIFICATION
Protein G affinity purified.
MOLECULAR WEIGHT
94 kDa
Isotype
IgG2a
APPLICATION DILUTION
-
IHC-P:1:100-1:500
TARGET
UNIPROT #
PROTEIN NAME
ddx24
SYNONYMS
DEAD (Asp-Glu-Ala-Asp) box helicase 24; ddx24
SUBCELLULAR LOCATION
Nucleolus.
FUNCTION
ATP-dependent RNA helicase DDX24 is an enzyme that in humans is encoded by the DDX24 gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial RNA splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.