Lane 1: Rat lung tissue lysate
Lane 2: MCF-7 cell lysate
Lane 3: Mouse lung tissue lysate
Rabbit polyclonal primary
Cytokeratin 19 Antibody (ER1803-79)
Recombinant protein within human cytokeratin 19 aa 100-350.
MCF-7, mouse lung tissue, HepG2, SK-Br-3, rat kidney tissue, human lung cancer tissue, human appendix tissue, human breast tissue, mouse colon tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Keratin, type I cytoskeletal 19
CK-19, K19, KRT19
Belongs to the intermediate filament family.
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Present in hair follicles at all stages of development.
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.