Rabbit polyclonal primary
CD42b Antibody (ER1803-26)
Recombinant protein with human cd42b aa 130-310.
Jurkat, human spleen tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
71 kDa (Predicted band size)
Platelet glycoprotein Ib alpha chain
GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, CD42b, GP1BA
Glycocalicin is the product of a proteolytic cleavage/shedding, catalyzed by ADAM17, which releases most of the extracellular domain. Binding sites for vWF and thrombin are in this part of the protein.
Membrane; Single-pass type I membrane protein.
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.