Rabbit polyclonal primary
CD35 Antibody (ER2001-14)
Recombinant protein within human complement receptor type 1 aa 600-800.
HL-60 cell lysates, recombinant protein lysates, human spleen tissue, human kidney tissue, Daudi.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Predicted band size: 224 kDa.
C3 binding protein antibody; C3b/C4b receptor antibody; C3BR antibody; C4BR antibody; CD 35 antibody; CD35 antibody; CD35 antigen antibody; complement component (3b/4b) receptor 1 (Knops blood group) antibody; complement component (3b/4b) receptor 1 including Knops blood group system antibody; Complement component receptor 1 antibody; Complement receptor 1 antibody; Complement receptor type 1 antibody; CR 1 antibody; CR1 antibody; CR1_HUMAN antibody; KN antibody; Knops blood group antigen antibody
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages . Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation . Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells .