Lane 1: K562 cell lysate
Lane 2: K562 cell lysate, the primary antibody was preincubated with immunization peptide.
Rabbit polyclonal primary
CD35 Antibody (ER1901-82)
Synthetic peptide within human cd35 aa 302-326.
K562 cell, 293T cell, F9 cell, HL-60 cell.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
C3 binding protein antibody; C3b/C4b receptor antibody; C3BR antibody; C4BR antibody; CD 35 antibody; CD35 antibody; CD35 antigen antibody; complement component (3b/4b) receptor 1 (Knops blood group) antibody; complement component (3b/4b) receptor 1 including Knops blood group system antibody; Complement component receptor 1 antibody; Complement receptor 1 antibody; Complement receptor type 1 antibody; CR 1 antibody; CR1 antibody; CR1_HUMAN antibody; KN antibody; Knops blood group antigen antibody
Belongs to the receptors of complement activation (RCA) family.
Present on erythrocytes, a subset of T cells, mature B cells, follicular dendritic cells, monocytes and granulocytes.
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells.