PRODUCT CODE: 0804-3

CD24 Antibody (0804-3)

Applications

  • WB

REACTIVITY

  • Mouse

  • Rat

Western blot analysis on mouse brain membrane using anti-CD24 polyclonal antibody.
  • Western blot analysis on mouse brain membrane using anti-CD24 polyclonal antibody.
Western blot analysis on mouse brain membrane using anti-CD24 polyclonal antibody.

Applications

  • WB

REACTIVITY

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

CD24 Antibody (0804-3)

Immunogen

Peptide

Host

Rabbit

Positive Control

Mouse brain tissue

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Immunogen affinity purified

MOLECULAR WEIGHT

37kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000

TARGET

UNIPROT #

PROTEIN NAME

CD24

SYNONYMS

CD 24 antibody; CD24 antibody; CD24 antigen (small cell lung carcinoma cluster 4 antigen) antibody; CD24 antigen antibody; CD24 molecule antibody; CD24_HUMAN antibody; CD24A antibody; FLJ22950 antibody; FLJ43543 antibody; GPI linked surface mucin antibody; Heat stable antigen antibody; HSA antibody; MGC75043 antibody; Nectadrin antibody; Signal transducer CD24 antibody; Small cell lung carcinoma cluster 4 antigen antibody

SEQUENCE SIMILARITIES

Belongs to the CD24 family.

TISSUE SPECIFICITY

In lymphoid, myeloid, and erythroid cells.

POST-TRANSLATIONAL MODIFICATION

The identity of the N- and O-linked polysaccharides are not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc.

SUBCELLULAR LOCATION

Cell membrane

FUNCTION

The CD24 antigen is a small heavily glycosylated, glycosylphosphatidylinositol (GPI) linked cell surface protein. It consists of a small protein core comprising 27 amino acids, which is extensively glycosylated and is bound to the membrane via a phosphatidylinositol anchor. The CD24 antigen is physiologically expressed in developing or regenerating tissue, as well as in granulocytes, keratinocytes and renal tubular epithelium. It modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.