Mouse monoclonal primary
CD1A Mouse Monoclonal Antibody [A3F9] (EM1901-89)
Recombinant protein within human cd1a aa 50-250.
K562 cell lysates, human skin tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein G affinity purified.
CD 1a antibody; CD1 antibody; CD1a antibody; CD1A Antigen antibody; CD1A antigen, a polypeptide antibody; CD1a molecule antibody; CD1A_HUMAN antibody; cluster of differentiation 1 A antibody; cortical thymocyte antigen CD1A antibody; differentiation antigen CD1 alpha 3 antibody; epidermal dendritic cell marker CD1a antibody; FCB 6 antibody; FCB6 antibody; HTA 1 antibody; HTA1 antibody; hTa1 thymocyte antigen antibody; OTTHUMP00000018907 antibody; R 4 antibody; R4 antibody; T 6 antibody; T-cell surface antigen T6/Leu-6 antibody; T-cell surface glycoprotein CD1a antibody; T6 antibody
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
Cell membrane, endosome membrane, membrane raft.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.