Mouse monoclonal primary
CD166 Monoclonal Antibody (EM1902-37)
Recombinant protein within human aa 1-400.
SW480 cell lysates, human lung cancer tissue, THP-1.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Predicted band size: 55 kDa.
Tyrosine-protein phosphatase non-receptor type substrate 1 SHP substrate 1 SHPS-1 Brain Ig-like molecule with tyrosine-based activation motifs Bit CD172 antigen-like family member A Inhibitory receptor SHPS-1 Macrophage fusion receptor MyD-1 antigen Signal-regulatory protein alpha-1 Sirp-alpha-1 Signal-regulatory protein alpha-2 Sirp-alpha-2 Signal-regulatory protein alpha-3 Sirp-alpha-3 p84 CD172a SIRPA
Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.