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CD134/OX40 Mouse Monoclonal Antibody [2H2] (EM1701-25)

Price: Regular price $325.00

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Catalog# EM1701-25

Mouse Monoclonal to CD134/OX40

Tested for

  • WB

  • IHC-P

  • ICC

  • FC

React with

  • Human

  • Mouse

  • Rat

Specifications

Product Type

Mouse monoclonal primary

Product Name

CD134/OX40 Mouse Monoclonal Antibody [2H2] (EM1701-25)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

A549 cells, Hela cells, HepG2 cells, human tonsil tissue, human spleen tissue, mouse spleen tissue, HL-60 cells.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

2H2

APPLICATION DILUTION

  • ICC

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

  • WB

  • 1:500

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 29 kDa

Isotype

IgG1

TARGET

UNIPROT #

P43489

PROTEIN NAME

CD134/OX40

SYNONYMS

ACT 35 antibody;ACT35 antibody;ACT35 antigen antibody;ATC35 antigen antibody;CD 134 antibody;CD134 antibody;CD134 antigen antibody;IMD16 antibody;Lymphoid activation antigene ACT35 antibody;OX 40 antibody;OX40 antibody;OX40 antigen antibody;OX40 cell surface antigen antibody;OX40 homologue antibody;OX40L receptor antibody;TAX transcriptionally activated glycoprotein 1 receptor antibody;TAX transcriptionally-activated glycoprotein 1 receptor antibody;TNF receptor superfamily member 4 antibody;TNFRSF 4 antibody;TNFRSF4 antibody;TNR4_HUMAN antibody;Tumor necrosis factor receptor superfamily member 4 antibody;Txgp 1l antibody;Txgp1 antibody;Txgp1l antibody

SUBCELLULAR LOCATION

Membrane.

FUNCTION

Ox40 (also designated CD134 and Ox40R), is a member of the tumor necrosis factor receptor (TNFR) family. Ox40 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. Ox40 is also involved in the stimulation of T cells, T cell-dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. Ox40 is expressed on activated CD4+ T lymphocytes and its ligand, Ox40L, is found preferentially on activated B cells. Engagement of Ox40 with its ligand, Ox40L, delivers a strong costimulatory signal to effector T cells. Members of the TNFR superfamily are critically involved in the regulation of infections, inflammation, autoimmune diseases and tissue homeostasis.

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