Mouse monoclonal primary
CD134/OX40 Mouse Monoclonal Antibody [2H2] (EM1701-25)
A549, Hela, HepG2, human tonsil tissue, human spleen tissue, mouse spleen tissue, HL-60.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
ACT 35 antibody; ACT35 antibody; ACT35 antigen antibody; ATC35 antigen antibody; CD 134 antibody; CD134 antibody; CD134 antigen antibody; IMD16 antibody; Lymphoid activation antigene ACT35 antibody; OX 40 antibody; OX40 antibody; OX40 antigen antibody; OX40 cell surface antigen antibody; OX40 homologue antibody; OX40L receptor antibody; TAX transcriptionally activated glycoprotein 1 receptor antibody; TAX transcriptionally-activated glycoprotein 1 receptor antibody; TNF receptor superfamily member 4 antibody; TNFRSF 4 antibody; TNFRSF4 antibody; TNR4_HUMAN antibody; Tumor necrosis factor receptor superfamily member 4 antibody; Txgp 1l antibody; Txgp1 antibody; Txgp1l antibody
Ox40 (also designated CD134 and Ox40R), is a member of the tumor necrosis factor receptor (TNFR) family. Ox40 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. Ox40 is also involved in the stimulation of T cells, T cell-dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. Ox40 is expressed on activated CD4+ T lymphocytes and its ligand, Ox40L, is found preferentially on activated B cells. Engagement of Ox40 with its ligand, Ox40L, delivers a strong costimulatory signal to effector T cells. Members of the TNFR superfamily are critically involved in the regulation of infections, inflammation, autoimmune diseases and tissue homeostasis.