UNIPROT #

P04040

PROTEIN NAME

Catalase

SYNONYMS

Cas1 antibody; CAT antibody; CATA_HUMAN antibody; Catalase antibody; Cs1 antibody; MGC138422 antibody; MGC138424 antibody

SEQUENCE SIMILARITIES

Belongs to the catalase family.

POST-TRANSLATIONAL MODIFICATION

The N-terminus is blocked.

SUBCELLULAR LOCATION

Peroxisome

FUNCTION

Hydrogen peroxide is a harmful byproduct of many normal metabolic processes; to prevent damage to cells and tissues, it must be quickly converted into other, less dangerous substances. To this end, catalase is frequently used by cells to rapidly catalyze the decomposition of hydrogen peroxide into less-reactive gaseous oxygen and water molecules. Catalase is usually located in a cellular, bipolar environment organelle called the peroxisome. All known animals use catalase in every organ, with particularly high concentrations occurring in the liver. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.