Positive control:
Lane 1: F9
Lane 2: A549
Lane 3: Mouse lung
Lane 4: Mouse liver
Lane 5: Human lung
Lane 6: Hela
Lane 7: HepG2
Lane 8: Jurkat
Applications
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WB
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ICC
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IHC-P
REACTIVITY
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Human
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Mouse
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Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
Catalase Antibody (ER40125)
Immunogen
Synthetic peptide (klh-coupled) within human caveolin-1 110-180aa.
Host
Rabbit
Positive Control
Hela, HepG2, A431, mouse liver tissue, mouse kidney tissue, human liver tissue, rat kidney tissue, rat liver tissue, rat lung tissue
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Peptide affinity purified
MOLECULAR WEIGHT
60 kDa
Isotype
IgG
APPLICATION DILUTION
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WB
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1:1,000
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ICC
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1:200
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IHC-P
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1:200
TARGET
UNIPROT #
PROTEIN NAME
Catalase
SYNONYMS
Cas1 antibody; CAT antibody; CATA_HUMAN antibody; Catalase antibody; Cs1 antibody; MGC138422 antibody; MGC138424 antibody
SEQUENCE SIMILARITIES
Belongs to the catalase family.
POST-TRANSLATIONAL MODIFICATION
The N-terminus is blocked.
SUBCELLULAR LOCATION
Peroxisome
FUNCTION
Hydrogen peroxide is a harmful byproduct of many normal metabolic processes; to prevent damage to cells and tissues, it must be quickly converted into other, less dangerous substances. To this end, catalase is frequently used by cells to rapidly catalyze the decomposition of hydrogen peroxide into less-reactive gaseous oxygen and water molecules. Catalase is usually located in a cellular, bipolar environment organelle called the peroxisome. All known animals use catalase in every organ, with particularly high concentrations occurring in the liver. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
CITATIONS
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Li, Kaiqun et al.
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-�B signaling. | Journal of Cellular Physiology [2019]
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WB
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mouse
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Citation
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