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PRODUCT CODE: ER1803-29

CACNB1 Antibody (ER1803-29)

Applications

  • WB

  • IHC-P

  • ICC

REACTIVITY

  • Human

  • Mouse

  • Rat

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Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.<br /> Lane 1: SH-SY-5Y cell lysate<br /> Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide
  • Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.<br /> Lane 1: SH-SY-5Y cell lysate<br /> Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide
  • Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.
Lane 1: SH-SY-5Y cell lysate
Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide

Applications

  • WB

  • IHC-P

  • ICC

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

CACNB1 Antibody (ER1803-29)

Immunogen

Synthetic peptide within rat cacnb1 aa 430-490.

Host

Rabbit

Positive Control

SH-SY-5Y, rat heart tissue, human tonsil tissue, human kidney tissue, human fetal skeletal muscle tissue, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified.

MOLECULAR WEIGHT

66/58/53 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

  • ICC

  • 1:50

TARGET

UNIPROT #

Q02641

PROTEIN NAME

CACNB1

SYNONYMS

CAB1 antibody; CACB1_HUMAN antibody; CACNB1 antibody; CACNLB1 antibody; Calcium channel L type beta 1 polypeptide antibody; Calcium channel voltage dependent beta 1 subunit antibody; Calcium channel voltage-dependent subunit beta 1 antibody; CCHLB1 antibody; Dihydropyridine sensitive L type calcium channel beta 1 subunit antibody; MGC41896 antibody; Voltage dependent L type calcium channel beta 1 subunit antibody; Voltage-dependent L-type calcium channel subunit beta-1 antibody

SEQUENCE SIMILARITIES

Belongs to the calcium channel beta subunit family.

TISSUE SPECIFICITY

Detected in heart ventricle (at protein level). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.

SUBCELLULAR LOCATION

Plasma membrane.

FUNCTION

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.