PRODUCT CODE: ER1803-29

CACNB1 Antibody (ER1803-29)

Applications

  • WB

  • IHC-P

  • ICC

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.<br />
 Lane 1: SH-SY-5Y cell lysate<br />
 Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide<br />
  • Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.<br />
 Lane 1: SH-SY-5Y cell lysate<br />
 Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide<br />
  • Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-CACNB1 antibody. Counter stained with hematoxylin.
Western blot analysis of CACNB1 on SH-SY-5Y cell lysate using anti-CACNB1 antibody at 1/1,000 dilution.
Lane 1: SH-SY-5Y cell lysate
Lane 2: SH-SY-5Y cell lysate with immunizaiton peptide

Applications

  • WB

  • IHC-P

  • ICC

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

CACNB1 Antibody (ER1803-29)

Immunogen

Synthetic peptide within rat cacnb1 aa 430-490.

Host

Rabbit

Positive Control

SH-SY-5Y, rat heart tissue, human tonsil tissue, human kidney tissue, human fetal skeletal muscle tissue, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified.

MOLECULAR WEIGHT

66/58/53 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

  • ICC

  • 1:50

TARGET

UNIPROT #

PROTEIN NAME

Voltage-dependent L-type calcium channel subunit beta-1

GENE NAME

CACNB1

SYNONYMS

CAB1, CACNB1, CACNLB1

SEQUENCE SIMILARITIES

Belongs to the calcium channel beta subunit family.

TISSUE SPECIFICITY

Detected in heart ventricle (at protein level). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.

SUBCELLULAR LOCATION

Cell membrane, sarcolemma; Peripheral membrane protein; Peripheral membrane protein.

FUNCTION

Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity). Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit.