UNIPROT #

P02768

PROTEIN NAME

Albumin

SYNONYMS

alb antibody; ALBU_HUMAN antibody; Albumin (32 AA) antibody; Albumin (AA 34) antibody; cell growth inhibiting protein 42 antibody; DKFZp779N1935 antibody; GIG20 antibody; GIG42 antibody; growth-inhibiting protein 20 antibody; OTTHUMP00000220436 antibody; OTTHUMP00000220438 antibody; OTTHUMP00000220439 antibody; PRO0883 antibody; PRO0903 antibody; PRO1341 antibody; PRO1708 antibody; PRO2044 antibody; PRO2619 antibody; PRO2675 antibody; Serum albumin antibody; UNQ696/PRO1341 antibody

SEQUENCE SIMILARITIES

Belongs to the ALB/AFP/VDB family.

TISSUE SPECIFICITY

Plasma.

POST-TRANSLATIONAL MODIFICATION

Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.; Glycated in diabetic patients.; Phosphorylated by FAM20C in the extracellular medium.; Acetylated on Lys-223 by acetylsalicylic acid.

SUBCELLULAR LOCATION

Secreted

FUNCTION

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Albumin is essential for maintaining the osmotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids.