Mouse monoclonal primary
CCDC47 Monoclonal Antibody (M1004-3)
Recombinant protein, F9, MCF-7, human liver tissue, human lung tissue, human testis tissue, human breast tissue, human colon tissue, human stomach tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
CCD47_HUMAN antibody; CCDC 47 antibody; CCDC47 antibody; Coiled coil domain containing 47 antibody; Coiled coil domain containing protein 47 antibody; Coiled-coil domain-containing protein 47 antibody; GK001 antibody; MSTP041 antibody
Coiled-coil domain 47 (CCDC47) is a gene located on human chromosome 17, specifically locus 17q23.3 which encodes for the protein CCDC47. The gene has several aliases including GK001 and MSTP041. The protein itself contains coiled-coil domains, the SEEEED superfamily, a domain of unknown function (DUF1682) and a transmembrane domain. The function of the protein is unknown, but it has been proposed that CCDC47 is involved in calcium ion homeostasis and the endoplasmic reticulum overload response. In addition to the high levels of phosphorylation seen in CCDC47, three sulfination sites are predicted and conserved in mammals, reptiles and birds but not in fish, amphibians or invertebrates. Five potential sumoylation sites are also seen and conserved back to the bony fish. There is no glycosylation of the protein as it is not predicted to extend into the extracellular portion of the cell.